node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIT05540.1 | AIT06735.1 | MC45_03005 | MC45_10555 | Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.914 |
AIT05540.1 | AIT07493.1 | MC45_03005 | MC45_15205 | Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
AIT05540.1 | mazG | MC45_03005 | MC45_03055 | Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | Nucleoside triphosphate hydrolase; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
AIT05540.1 | nadD | MC45_03005 | MC45_15100 | Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.941 |
AIT05540.1 | nadE | MC45_03005 | MC45_06665 | Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.538 |
AIT05540.1 | pncB | MC45_03005 | MC45_07810 | Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.921 |
AIT06303.1 | pncB | MC45_07815 | MC45_07810 | GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.547 |
AIT06735.1 | AIT05540.1 | MC45_10555 | MC45_03005 | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | 0.914 |
AIT06735.1 | AIT07230.1 | MC45_10555 | MC45_13595 | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.583 |
AIT06735.1 | AIT07493.1 | MC45_10555 | MC45_15205 | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
AIT06735.1 | mazG | MC45_10555 | MC45_03055 | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Nucleoside triphosphate hydrolase; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.902 |
AIT06735.1 | nadD | MC45_10555 | MC45_15100 | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.932 |
AIT06735.1 | nadE | MC45_10555 | MC45_06665 | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.550 |
AIT06735.1 | pncB | MC45_10555 | MC45_07810 | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.942 |
AIT07230.1 | AIT06735.1 | MC45_13595 | MC45_10555 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.583 |
AIT07230.1 | nadD | MC45_13595 | MC45_15100 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.709 |
AIT07230.1 | nadE | MC45_13595 | MC45_06665 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.753 |
AIT07230.1 | pncB | MC45_13595 | MC45_07810 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.529 |
AIT07230.1 | polA | MC45_13595 | MC45_13670 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.553 |
AIT07493.1 | AIT05540.1 | MC45_15205 | MC45_03005 | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. | 0.902 |