node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APC41420.1 | def-3 | A7L45_15720 | A7L45_15715 | B12-binding domain-containing radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.713 |
def-3 | APC41420.1 | A7L45_15715 | A7L45_15720 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | B12-binding domain-containing radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.713 |
def-3 | rplD | A7L45_15715 | A7L45_20905 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.718 |
def-3 | rplI | A7L45_15715 | A7L45_21845 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.711 |
def-3 | rplM | A7L45_15715 | A7L45_20735 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.709 |
def-3 | rplS | A7L45_15715 | A7L45_13105 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.721 |
def-3 | rplT | A7L45_15715 | A7L45_17445 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.754 |
def-3 | rplU | A7L45_15715 | A7L45_15230 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.755 |
def-3 | rpsO | A7L45_15715 | A7L45_12940 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.711 |
def-3 | rpsT | A7L45_15715 | A7L45_15135 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.707 |
def-3 | tig | A7L45_15715 | A7L45_19140 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.714 |
rplD | def-3 | A7L45_20905 | A7L45_15715 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.718 |
rplD | rplI | A7L45_20905 | A7L45_21845 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.979 |
rplD | rplM | A7L45_20905 | A7L45_20735 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.995 |
rplD | rplS | A7L45_20905 | A7L45_13105 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.986 |
rplD | rplT | A7L45_20905 | A7L45_17445 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.987 |
rplD | rplU | A7L45_20905 | A7L45_15230 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.979 |
rplD | rpsO | A7L45_20905 | A7L45_12940 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.998 |
rplD | rpsT | A7L45_20905 | A7L45_15135 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.939 |
rplD | tig | A7L45_20905 | A7L45_19140 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.954 |