STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DL764_007505Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (819 aa)    
Predicted Functional Partners:
MDM34
Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
   
 0.938
DL764_000225
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.938
DL764_002947
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
   
  0.933
DL764_009250
Uncharacterized protein.
    
  0.931
DL764_006886
Uncharacterized protein.
    
 0.885
DL764_005132
U3 small nucleolar RNA-associated protein 22.
   
 0.880
DL764_002149
Uncharacterized protein.
    
  0.851
DL764_006645
RNA helicase.
   
   0.803
DL764_010906
Uncharacterized protein.
   
 
 0.771
DL764_007735
S4 RNA-binding domain-containing protein.
   
   0.737
Your Current Organism:
Monosporascus ibericus
NCBI taxonomy Id: 155417
Other names: AG224, CBS 110550, M. ibericus, MA Fungi 48050, Monosporascus ibericus Collado, Ant. Gonzalez, Stchigel, Guarro & Pelaez, 2002
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