STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (341 aa)    
Predicted Functional Partners:
GET1
Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
    
 0.996
DL764_001527
Uncharacterized protein.
    
 0.993
DL764_006082
Uncharacterized protein.
   
 0.973
DL764_007930
Uncharacterized protein.
    
 0.970
DL764_007868
Uncharacterized protein.
    
 0.959
DL764_005924
TPR_REGION domain-containing protein.
   
 0.929
DL764_008259
LMWPc domain-containing protein.
    
 0.916
DL764_002094
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.860
DL764_003092
t-SNARE coiled-coil homology domain-containing protein.
   
 0.852
DL764_003740
Uncharacterized protein; Belongs to the synaptobrevin family.
   
 
 0.837
Your Current Organism:
Monosporascus ibericus
NCBI taxonomy Id: 155417
Other names: AG224, CBS 110550, M. ibericus, MA Fungi 48050, Monosporascus ibericus Collado, Ant. Gonzalez, Stchigel, Guarro & Pelaez, 2002
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.