STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DL764_006147AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (986 aa)    
Predicted Functional Partners:
DL764_003555
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.993
DL764_002541
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.993
DL764_007249
AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.962
DL764_005974
Ubiquitin-like domain-containing protein.
   
 0.941
DL764_001596
AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.941
DL764_002459
DUF1681 domain-containing protein.
    
  0.935
DL764_004439
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.920
DL764_005093
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.914
DL764_010587
Uncharacterized protein.
   
 0.871
DL764_002098
ENTH domain-containing protein.
    
 0.867
Your Current Organism:
Monosporascus ibericus
NCBI taxonomy Id: 155417
Other names: AG224, CBS 110550, M. ibericus, MA Fungi 48050, Monosporascus ibericus Collado, Ant. Gonzalez, Stchigel, Guarro & Pelaez, 2002
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.