node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
JP36_00255 | JP36_00390 | JP36_00255 | JP36_00390 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Arabinose 5-phosphate isomerase. | 0.702 |
JP36_00255 | JP36_10860 | JP36_00255 | JP36_10860 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.716 |
JP36_00255 | adk | JP36_00255 | JP36_09735 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.889 |
JP36_00255 | gltB | JP36_00255 | JP36_08170 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate. | 0.684 |
JP36_00255 | guaA | JP36_00255 | JP36_02040 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.852 |
JP36_00255 | guaB | JP36_00255 | JP36_02050 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.824 |
JP36_00255 | hflB | JP36_00255 | JP36_10520 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.747 |
JP36_00255 | purA | JP36_00255 | JP36_00590 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.691 |
JP36_00255 | purH | JP36_00255 | JP36_03080 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis. | 0.675 |
JP36_00255 | tilS | JP36_00255 | JP36_03540 | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.730 |
JP36_00390 | JP36_00255 | JP36_00390 | JP36_00255 | Arabinose 5-phosphate isomerase. | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.702 |
JP36_00390 | JP36_10860 | JP36_00390 | JP36_10860 | Arabinose 5-phosphate isomerase. | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.409 |
JP36_00390 | adk | JP36_00390 | JP36_09735 | Arabinose 5-phosphate isomerase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.667 |
JP36_00390 | gltB | JP36_00390 | JP36_08170 | Arabinose 5-phosphate isomerase. | Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate. | 0.851 |
JP36_00390 | guaA | JP36_00390 | JP36_02040 | Arabinose 5-phosphate isomerase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.950 |
JP36_00390 | guaB | JP36_00390 | JP36_02050 | Arabinose 5-phosphate isomerase. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.869 |
JP36_00390 | purA | JP36_00390 | JP36_00590 | Arabinose 5-phosphate isomerase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.677 |
JP36_00390 | purH | JP36_00390 | JP36_03080 | Arabinose 5-phosphate isomerase. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis. | 0.806 |
JP36_00390 | tilS | JP36_00390 | JP36_03540 | Arabinose 5-phosphate isomerase. | Hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.422 |
JP36_10860 | JP36_00255 | JP36_10860 | JP36_00255 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.716 |