node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
JP36_01460 | bioA | JP36_01460 | JP36_01455 | ATP-dependent helicase HrpA; Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.781 |
JP36_03805 | JP36_06550 | JP36_03805 | JP36_06550 | 8-amino-7-oxononanoate synthase. | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.464 |
JP36_03805 | JP36_11030 | JP36_03805 | JP36_11030 | 8-amino-7-oxononanoate synthase. | Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.740 |
JP36_03805 | bioA | JP36_03805 | JP36_01455 | 8-amino-7-oxononanoate synthase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.953 |
JP36_03805 | bioB | JP36_03805 | JP36_03635 | 8-amino-7-oxononanoate synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.900 |
JP36_03805 | bioC | JP36_03805 | JP36_03815 | 8-amino-7-oxononanoate synthase. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.935 |
JP36_03805 | bioD | JP36_03805 | JP36_00215 | 8-amino-7-oxononanoate synthase. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.920 |
JP36_03805 | bioD-2 | JP36_03805 | JP36_01535 | 8-amino-7-oxononanoate synthase. | ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.931 |
JP36_06550 | JP36_03805 | JP36_06550 | JP36_03805 | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 8-amino-7-oxononanoate synthase. | 0.464 |
JP36_06550 | JP36_11030 | JP36_06550 | JP36_11030 | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.954 |
JP36_06550 | bioA | JP36_06550 | JP36_01455 | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.813 |
JP36_06550 | metL | JP36_06550 | JP36_00790 | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Aspartate kinase; Multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways. | 0.415 |
JP36_06550 | thrA | JP36_06550 | JP36_02415 | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways. | 0.415 |
JP36_11030 | JP36_03805 | JP36_11030 | JP36_03805 | Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 8-amino-7-oxononanoate synthase. | 0.740 |
JP36_11030 | JP36_06550 | JP36_11030 | JP36_06550 | Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.954 |
JP36_11030 | bioA | JP36_11030 | JP36_01455 | Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.820 |
JP36_11030 | metL | JP36_11030 | JP36_00790 | Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Aspartate kinase; Multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways. | 0.825 |
JP36_11030 | thrA | JP36_11030 | JP36_02415 | Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways. | 0.825 |
bioA | JP36_01460 | JP36_01455 | JP36_01460 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | ATP-dependent helicase HrpA; Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain. | 0.781 |
bioA | JP36_03805 | JP36_01455 | JP36_03805 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 8-amino-7-oxononanoate synthase. | 0.953 |