node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
JP36_00230 | JP36_02610 | JP36_00230 | JP36_02610 | Membrane protein. | acyl-CoA thioester hydrolase. | 0.437 |
JP36_00230 | JP36_06545 | JP36_00230 | JP36_06545 | Membrane protein. | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.561 |
JP36_00230 | JP36_06550 | JP36_00230 | JP36_06550 | Membrane protein. | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.566 |
JP36_00230 | acsA | JP36_00230 | JP36_08130 | Membrane protein. | 3-hydroxypropionyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.508 |
JP36_00230 | sucC | JP36_00230 | JP36_09620 | Membrane protein. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.503 |
JP36_02605 | JP36_02610 | JP36_02605 | JP36_02610 | Hypothetical protein; Unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity. | acyl-CoA thioester hydrolase. | 0.793 |
JP36_02605 | JP36_02615 | JP36_02605 | JP36_02615 | Hypothetical protein; Unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity. | Septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. | 0.793 |
JP36_02605 | JP36_02620 | JP36_02605 | JP36_02620 | Hypothetical protein; Unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity. | Hypothetical protein. | 0.773 |
JP36_02605 | dsbD | JP36_02605 | JP36_02625 | Hypothetical protein; Unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity. | Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.668 |
JP36_02610 | JP36_00230 | JP36_02610 | JP36_00230 | acyl-CoA thioester hydrolase. | Membrane protein. | 0.437 |
JP36_02610 | JP36_02605 | JP36_02610 | JP36_02605 | acyl-CoA thioester hydrolase. | Hypothetical protein; Unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity. | 0.793 |
JP36_02610 | JP36_02615 | JP36_02610 | JP36_02615 | acyl-CoA thioester hydrolase. | Septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. | 0.793 |
JP36_02610 | JP36_02620 | JP36_02610 | JP36_02620 | acyl-CoA thioester hydrolase. | Hypothetical protein. | 0.773 |
JP36_02610 | JP36_06545 | JP36_02610 | JP36_06545 | acyl-CoA thioester hydrolase. | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.612 |
JP36_02610 | JP36_06550 | JP36_02610 | JP36_06550 | acyl-CoA thioester hydrolase. | Fatty-acid oxidation protein subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.861 |
JP36_02610 | JP36_09125 | JP36_02610 | JP36_09125 | acyl-CoA thioester hydrolase. | Hypothetical protein. | 0.592 |
JP36_02610 | acsA | JP36_02610 | JP36_08130 | acyl-CoA thioester hydrolase. | 3-hydroxypropionyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.634 |
JP36_02610 | dsbD | JP36_02610 | JP36_02625 | acyl-CoA thioester hydrolase. | Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.543 |
JP36_02610 | sucC | JP36_02610 | JP36_09620 | acyl-CoA thioester hydrolase. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.553 |
JP36_02615 | JP36_02605 | JP36_02615 | JP36_02605 | Septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. | Hypothetical protein; Unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity. | 0.793 |