node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
JP36_04595 | JP36_05960 | JP36_04595 | JP36_05960 | Hypothetical protein. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.432 |
JP36_04595 | JP36_05970 | JP36_04595 | JP36_05970 | Hypothetical protein. | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.401 |
JP36_04595 | JP36_10445 | JP36_04595 | JP36_10445 | Hypothetical protein. | BadM/Rrf2 family transcriptional regulator. | 0.401 |
JP36_04595 | iscS | JP36_04595 | JP36_05965 | Hypothetical protein. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.419 |
JP36_04595 | nfuA | JP36_04595 | JP36_04530 | Hypothetical protein. | Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.816 |
JP36_05960 | JP36_04595 | JP36_05960 | JP36_04595 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Hypothetical protein. | 0.432 |
JP36_05960 | JP36_05970 | JP36_05960 | JP36_05970 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.971 |
JP36_05960 | JP36_10445 | JP36_05960 | JP36_10445 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | BadM/Rrf2 family transcriptional regulator. | 0.696 |
JP36_05960 | iscS | JP36_05960 | JP36_05965 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.999 |
JP36_05960 | nfuA | JP36_05960 | JP36_04530 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.978 |
JP36_05960 | thiI | JP36_05960 | JP36_05220 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | tRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.541 |
JP36_05970 | JP36_04595 | JP36_05970 | JP36_04595 | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Hypothetical protein. | 0.401 |
JP36_05970 | JP36_05960 | JP36_05970 | JP36_05960 | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.971 |
JP36_05970 | JP36_10445 | JP36_05970 | JP36_10445 | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | BadM/Rrf2 family transcriptional regulator. | 0.422 |
JP36_05970 | iscS | JP36_05970 | JP36_05965 | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.970 |
JP36_05970 | nfuA | JP36_05970 | JP36_04530 | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.627 |
JP36_05970 | thiI | JP36_05970 | JP36_05220 | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | tRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.409 |
JP36_10445 | JP36_04595 | JP36_10445 | JP36_04595 | BadM/Rrf2 family transcriptional regulator. | Hypothetical protein. | 0.401 |
JP36_10445 | JP36_05960 | JP36_10445 | JP36_05960 | BadM/Rrf2 family transcriptional regulator. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.696 |
JP36_10445 | JP36_05970 | JP36_10445 | JP36_05970 | BadM/Rrf2 family transcriptional regulator. | Transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.422 |