node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A4P9WYC4 | A0A4P9X7N9 | A0A4P9WYC4 | A0A4P9X7N9 | dUTP diphosphatase. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.952 |
A0A4P9WYC4 | A0A4P9X9A4 | A0A4P9WYC4 | A0A4P9X9A4 | dUTP diphosphatase. | UPF0029 domain-containing protein. | 0.714 |
A0A4P9WYC4 | A0A4P9XAM8 | A0A4P9WYC4 | A0A4P9XAM8 | dUTP diphosphatase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.905 |
A0A4P9WYC4 | CXG81DRAFT_128 | A0A4P9WYC4 | A0A4P9X846 | dUTP diphosphatase. | Thymidylate_kin domain-containing protein. | 0.922 |
A0A4P9X2U9 | A0A4P9X7N9 | A0A4P9X2U9 | A0A4P9X7N9 | Dihydrolipoyl dehydrogenase. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.904 |
A0A4P9X2U9 | A0A4P9X812 | A0A4P9X2U9 | A0A4P9X812 | Dihydrolipoyl dehydrogenase. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.805 |
A0A4P9X2U9 | A0A4P9X9A4 | A0A4P9X2U9 | A0A4P9X9A4 | Dihydrolipoyl dehydrogenase. | UPF0029 domain-containing protein. | 0.686 |
A0A4P9X2U9 | A0A4P9XAS7 | A0A4P9X2U9 | A0A4P9XAS7 | Dihydrolipoyl dehydrogenase. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.990 |
A0A4P9X7N9 | A0A4P9WYC4 | A0A4P9X7N9 | A0A4P9WYC4 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | dUTP diphosphatase. | 0.952 |
A0A4P9X7N9 | A0A4P9X2U9 | A0A4P9X7N9 | A0A4P9X2U9 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | Dihydrolipoyl dehydrogenase. | 0.904 |
A0A4P9X7N9 | A0A4P9X812 | A0A4P9X7N9 | A0A4P9X812 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.910 |
A0A4P9X7N9 | A0A4P9X9A4 | A0A4P9X7N9 | A0A4P9X9A4 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | UPF0029 domain-containing protein. | 0.759 |
A0A4P9X7N9 | A0A4P9XAM8 | A0A4P9X7N9 | A0A4P9XAM8 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.917 |
A0A4P9X7N9 | A0A4P9XAS7 | A0A4P9X7N9 | A0A4P9XAS7 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.909 |
A0A4P9X7N9 | A0A4P9XFY6 | A0A4P9X7N9 | A0A4P9XFY6 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.904 |
A0A4P9X7N9 | CXG81DRAFT_128 | A0A4P9X7N9 | A0A4P9X846 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | Thymidylate_kin domain-containing protein. | 0.922 |
A0A4P9X812 | A0A4P9X2U9 | A0A4P9X812 | A0A4P9X2U9 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Dihydrolipoyl dehydrogenase. | 0.805 |
A0A4P9X812 | A0A4P9X7N9 | A0A4P9X812 | A0A4P9X7N9 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. | 0.910 |
A0A4P9X812 | A0A4P9X9A4 | A0A4P9X812 | A0A4P9X9A4 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | UPF0029 domain-containing protein. | 0.730 |
A0A4P9X812 | A0A4P9XAS7 | A0A4P9X812 | A0A4P9XAS7 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.806 |