STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yagROrf, hypothetical protein; Oxidizes aldehydes to the corresponding carboxylic acids with a preference for aromatic aldehydes. It might play a role in the detoxification of aldehydes to avoid cell damage. (732 aa)    
Predicted Functional Partners:
yagS
Orf, hypothetical protein; Oxidizes aldehydes to the corresponding carboxylic acids with a preference for aromatic aldehydes. It might play a role in the detoxification of aldehydes to avoid cell damage.
 0.999
yagT
Putative xanthine dehydrogenase; Oxidizes aldehydes to the corresponding carboxylic acids with a preference for aromatic aldehydes. It might play a role in the detoxification of aldehydes to avoid cell damage.
 0.999
xdhC
Putative dehydrogenase; Iron-sulfur subunit of the xanthine dehydrogenase complex.
 0.999
ygeT
Putative dehydrogenase; Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) (By similarity).
 0.993
yagQ
Orf, hypothetical protein; Residues 1 to 318 of 318 are 98.42 pct identical to residues 1 to 318 of 318 from Escherichia coli K-12 Strain MG1655: B0283.
 
  
 0.990
xdhA
Orf, hypothetical protein; Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) (By similarity).
  
  
 
0.925
ygfP
Orf, hypothetical protein; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
 
 0.906
yicP
Probable adenine deaminase (synthesis xanthine); Residues 1 to 588 of 588 are 98.97 pct identical to residues 1 to 588 of 588 from Escherichia coli K-12 Strain MG1655: B3665.
    
  0.905
gpt
Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
  0.901
hpt
Hypoxanthine phosphoribosyltransferase; Residues 1 to 182 of 182 are 100.00 pct identical to residues 1 to 182 of 182 from Escherichia coli K-12 Strain MG1655: B0125; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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