STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacZbeta-D-galactosidase; Residues 1 to 1024 of 1024 are 97.36 pct identical to residues 1 to 1024 of 1024 from Escherichia coli K-12 Strain MG1655: B0344; Belongs to the glycosyl hydrolase 2 family. (1024 aa)    
Predicted Functional Partners:
lacY
Galactoside permease (M protein); Residues 1 to 417 of 417 are 99.76 pct identical to residues 1 to 417 of 417 from Escherichia coli K-12 Strain MG1655: B0343.
 
  
 0.988
lacA
Thiogalactoside acetyltransferase; Residues 1 to 203 of 203 are 97.04 pct identical to residues 1 to 203 of 203 from Escherichia coli K-12 Strain MG1655: B0342.
 
  
 0.969
ebgC
Evolved beta-D-galactosidase, beta subunit; Residues 1 to 149 of 149 are 99.32 pct identical to residues 1 to 149 of 149 from Escherichia coli K-12 Strain MG1655: B3077.
   
  0.929
melA
Alpha-galactosidase; Residues 1 to 451 of 451 are 98.89 pct identical to residues 1 to 451 of 451 from Escherichia coli K-12 Strain MG1655: B4119.
 
  
 0.928
galM
Galactose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer.
 
 
 0.926
lacI
Transcriptional repressor of the lac operon; Residues 1 to 360 of 360 are 99.44 pct identical to residues 1 to 360 of 360 from Escherichia coli K-12 Strain MG1655: B0345.
 
   
 0.925
ebgA
Evolved beta-D-galactosidase, alpha subunit; Residues 1 to 1042 of 1042 are 99.23 pct identical to residues 1 to 1042 of 1042 from Escherichia coli K-12 Strain MG1655: B3076.
  
  
0.919
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.917
yihR
Putative aldose-1-epimerase; Residues 1 to 298 of 300 are 96.97 pct identical to residues 9 to 306 of 308 from Escherichia coli K-12 Strain MG1655: B3879.
  
 
 0.907
glk
Glucokinase; Not highly important in E.coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.
     
 0.901
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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