STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adhCAlcohol dehydrogenase class III; Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)    
Predicted Functional Partners:
yaiM
Putative esterase; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
 0.999
yeiG
Putative esterase; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
 0.999
yaiN
Putative alpha helix chain; Repressor of the frmRAB operon; Belongs to the FrmR/RcnR family.
  
  
 0.992
adhE
CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family.
  
 0.971
eutG
Ethanolamine utilization; Residues 1 to 404 of 404 are 99.25 pct identical to residues 1 to 404 of 404 from Escherichia coli K-12 Strain MG1655: B2453.
   
 0.957
yiaY
Putative oxidoreductase; Residues 1 to 381 of 383 are 98.95 pct identical to residues 1 to 381 of 382 from Escherichia coli K-12 Strain MG1655: B3589.
   
 0.957
yjgB
Putative oxidoreductase; Residues 1 to 353 of 353 are 99.15 pct identical to residues 1 to 353 of 353 from Escherichia coli K-12 Strain MG1655: B4269.
  
 
 0.943
yahK
Putative oxidoreductase; Residues 1 to 349 of 349 are 99.42 pct identical to residues 1 to 349 of 349 from Escherichia coli K-12 Strain MG1655: B0325.
  
 
0.937
adhP
Alcohol dehydrogenase; Residues 1 to 345 of 346 are 99.42 pct identical to residues 1 to 345 of 346 from Escherichia coli K-12 Strain MG1655: B1478.
  
 
0.937
aldB
Aldehyde dehydrogenase B (lactaldehyde dehydrogenase); Residues 1 to 542 of 542 are 99.26 pct identical to residues 1 to 542 of 542 from Escherichia coli K-12 Strain MG1655: B3588; Belongs to the aldehyde dehydrogenase family.
  
 0.914
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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