STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpmAPhosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase; Residues 1 to 387 of 387 are 99.74 pct identical to residues 1 to 387 of 387 from Escherichia coli K-12 Strain MG1655: B2926; Belongs to the phosphoglycerate kinase family.
   
 0.985
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 0.984
yibO
Putative 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.980
gpmB
Residues 1 to 215 of 215 are 99.53 pct identical to residues 1 to 215 of 215 from Escherichia coli K-12 Strain MG1655: B4395; Belongs to the phosphoglycerate mutase family. GpmB subfamily.
  
 
 0.952
pgi
Glucosephosphate isomerase; Residues 1 to 549 of 549 are 100.00 pct identical to residues 1 to 549 of 549 from Escherichia coli K-12 Strain MG1655: B4025; Belongs to the GPI family.
   
 
 0.944
serA
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.908
fba
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
 
 0.908
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.904
ybbZ
Orf, hypothetical protein; Residues 1 to 381 of 381 are 98.16 pct identical to residues 1 to 381 of 381 from Escherichia coli K-12 Strain MG1655: B0514; Belongs to the glycerate kinase type-1 family.
     
 0.902
yhaD
Orf, hypothetical protein; Residues 1 to 387 of 387 are 99.48 pct identical to residues 22 to 408 of 408 from Escherichia coli K-12 Strain MG1655: B3124; Belongs to the glycerate kinase type-1 family.
     
 0.902
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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