STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycaLPutative heat shock protein; Residues 1 to 262 of 262 are 99.23 pct identical to residues 1 to 262 of 262 from Escherichia coli K-12 Strain MG1655: B0909. (262 aa)    
Predicted Functional Partners:
bepA
Orf, hypothetical protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
  
  
 0.895
yibQ
Hypothetical protein; Residues 1 to 277 of 277 are 99.63 pct identical to residues 1 to 277 of 277 from Escherichia coli K-12 Strain MG1655: B3614.
      
 0.704
cmk
Cytidylate kinase; Residues 1 to 227 of 227 are 100.00 pct identical to residues 1 to 227 of 227 from Escherichia coli K-12 Strain MG1655: B0910.
 
     0.581
aroA
5-enolpyruvylshikimate-3-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.480
uidA_1
Partial beta-D-glucuronidase; Residues 1 to 368 of 368 are 99.18 pct identical to residues 236 to 603 of 603 from Escherichia coli K-12 Strain MG1655: B1617.
      
 0.461
lapB
Putative cytoplasmic membrane export protein; Residues 12 to 701 of 720 are 27.76 pct identical to residues 15 to 698 of 711 from GenPept 118 : gi|6531348|gb|AAF15371.1|U66588_3 (U66588) PaxB [Pasteurella aerogenes].
 
     0.449
rpsA
30S ribosomal subunit protein S1; Required for translation of most natural mRNAs except for leaderless mRNA. Binds mRNA upstream of the Shine-Dalgarno (SD) sequence and helps it bind to the 30S ribosomal subunit; acts as an RNA chaperone to unfold structured mRNA on the ribosome but is not essential for mRNAs with strong SDs and little 5'-UTR structure, thus it may help fine-tune which mRNAs that are translated. Unwinds dsRNA by binding to transiently formed ssRNA regions; binds about 10 nucleotides. Has a preference for polypyrimidine tracts. Negatively autoregulates its own translation.
 
    0.412
Z0608
Putative outer membrane export protein; Residues 29 to 413 of 451 are 25.81 pct identical to residues 45 to 442 of 474 from GenPept 118 : gi|39735|emb|CAA32414.1| (X14199) cyaE [Bordetella pertussis].
  
     0.409
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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