STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ompTOuter membrane protein 3b (a), protease VII; Protease that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins. This protease has a specificity for paired basic residues (By similarity). (317 aa)    
Predicted Functional Partners:
yaeQ
Hypothetical protein; Residues 1 to 152 of 152 are 99.34 pct identical to residues 1 to 152 of 181 from Escherichia coli K-12 Strain MG1655: B0190.
   
    0.947
Z2542
Hypothetical protein; Residues 1 to 278 of 527 are 95.68 pct identical to residues 1 to 278 of 631 from Escherichia coli K-12 Strain MG1655: B1268.
  
    0.939
tufA
Protein chain elongation factor EF-Tu (duplicate of tufB); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.936
tufB
Protein chain elongation factor EF-Tu (duplicate of tufA); Residues 1 to 394 of 394 are 99.49 pct identical to residues 1 to 394 of 394 from Escherichia coli K-12 Strain MG1655: B3980.
   
  
 0.925
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.900
cspC
Cold shock protein; Residues 1 to 69 of 69 are 100.00 pct identical to residues 1 to 69 of 69 from Escherichia coli K-12 Strain MG1655: B1823.
   
    0.892
minE
Cell division topological specificity factor, reverses MinC inhibition of ftsZ ring formation; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity).
   
    0.863
lepB
Leader peptidase (signal peptidase I); Residues 1 to 324 of 324 are 99.69 pct identical to residues 1 to 324 of 324 from Escherichia coli K-12 Strain MG1655: B2568; Belongs to the peptidase S26 family.
   
  
 0.859
yobF
Orf, hypothetical protein; Residues 1 to 47 of 47 are 100.00 pct identical to residues 1 to 47 of 47 from Escherichia coli K-12 Strain MG1655: B1824; Belongs to the YobF/DUF2527 family.
   
    0.855
yfiA
Putative yhbH sigma 54 modulator; During stationary phase, prevents 70S dimer formation, probably in order to regulate translation efficiency during transition between the exponential and the stationary phases. In addition, during environmental stress such as cold shock or excessive cell density at stationary phase, stabilizes the 70S ribosome against dissociation, inhibits translation initiation and increase translation accuracy. When normal growth conditions are restored, is quickly released from the ribosome (By similarity).
   
    0.854
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.