STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
minECell division topological specificity factor, reverses MinC inhibition of ftsZ ring formation; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity). (88 aa)    
Predicted Functional Partners:
minD
Cell division inhibitor, a membrane ATPase, activates minC; ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity).
 
 
 0.998
cspC
Cold shock protein; Residues 1 to 69 of 69 are 100.00 pct identical to residues 1 to 69 of 69 from Escherichia coli K-12 Strain MG1655: B1823.
   
    0.971
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.957
minC
Cell division inhibitor, inhibits ftsZ ring formation; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
  
 0.947
tufA
Protein chain elongation factor EF-Tu (duplicate of tufB); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
    0.938
yobF
Orf, hypothetical protein; Residues 1 to 47 of 47 are 100.00 pct identical to residues 1 to 47 of 47 from Escherichia coli K-12 Strain MG1655: B1824; Belongs to the YobF/DUF2527 family.
   
    0.926
yaeQ
Hypothetical protein; Residues 1 to 152 of 152 are 99.34 pct identical to residues 1 to 152 of 181 from Escherichia coli K-12 Strain MG1655: B0190.
   
    0.906
lepB
Leader peptidase (signal peptidase I); Residues 1 to 324 of 324 are 99.69 pct identical to residues 1 to 324 of 324 from Escherichia coli K-12 Strain MG1655: B2568; Belongs to the peptidase S26 family.
   
    0.903
rne
RNase E, membrane attachment, mRNA turnover, maturation 5S RNA; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
  
    0.899
tufB
Protein chain elongation factor EF-Tu (duplicate of tufA); Residues 1 to 394 of 394 are 99.49 pct identical to residues 1 to 394 of 394 from Escherichia coli K-12 Strain MG1655: B3980.
   
    0.895
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.