STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btuCVitamin B12 transport permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity). (326 aa)    
Predicted Functional Partners:
yadT
Orf, hypothetical protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
 
 
 0.999
btuD
ATP-binding component of vitamin B12 transport system; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
 
 
 0.999
btuE
Vitamin B12 transport; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.
    
 0.861
btuB
Outer membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
 
   
 0.851
fhuC
ATP-binding component of hydroxymate-dependent iron transport; Residues 1 to 265 of 265 are 99.62 pct identical to residues 1 to 265 of 265 from Escherichia coli K-12 Strain MG1655: B0151.
 
   
 0.777
chuT
Putative periplasmic binding protein; Residues 1 to 304 of 304 are 97.36 pct identical to residues 1 to 304 of 304 from GenPept 118 : gi|2967538|gb|AAC27815.1| (U64516) unknown [Shigella dysenteriae].
  
   
 0.769
hmuV
Putative ATP-binding protein of ABC transport system; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
  
     0.768
fepC
ATP-binding component of ferric enterobactin transport; Residues 1 to 271 of 271 are 99.63 pct identical to residues 1 to 271 of 271 from Escherichia coli K-12 Strain MG1655: B0588.
 
   
 0.767
fepC_2
Putative ATP-binding protein of ABC transporter family; Residues 2 to 263 of 269 are 49.23 pct identical to residues 13 to 274 of 279 from GenPept 118 : gi|5731362|gb|AAD48883.1| (U52150) ATPase [Vibrio cholerae].
 
   
 0.755
Z1966
Hypothetical protein; Residues 34 to 292 of 340 are 26.59 pct identical to residues 55 to 316 of 319 from GenPept 118 : gi|1124959|emb|CAA63627.1| (X93084) orf2 [Methanosarcina barkeri].
 
 
 
 0.671
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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