STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crrPTS system, glucose-specific IIA component; Residues 1 to 169 of 169 are 99.40 pct identical to residues 1 to 169 of 169 from Escherichia coli K-12 Strain MG1655: B2417. (169 aa)    
Predicted Functional Partners:
ptsG
PTS system, glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration.
 0.999
malX
PTS system, maltose and glucose-specific II ABC; Residues 1 to 530 of 530 are 99.43 pct identical to residues 1 to 530 of 530 from Escherichia coli K-12 Strain MG1655: B1621.
 0.999
ptsH
PTS system protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
 
 0.999
ptsI
PEP-protein phosphotransferase system enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
murP
Putative PTS enzyme II; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
 0.998
ascF
PTS system enzyme II ABC (asc), cryptic, transports specific beta-glucosides; Residues 1 to 485 of 485 are 97.93 pct identical to residues 1 to 485 of 485 from Escherichia coli K-12 Strain MG1655: B2715.
 0.998
glvC
Putative PTS component; Residues 1 to 370 of 540 are 99.45 pct identical to residues 86 to 455 of 455 from Escherichia coli K-12 Strain MG1655: B3683.
 0.998
treB
PTS system enzyme II, trehalose specific; Residues 1 to 473 of 473 are 99.57 pct identical to residues 1 to 473 of 473 from Escherichia coli K-12 Strain MG1655: B4240.
 0.997
fryA
Putative PTS system enzyme IIA component, enzyme I; Multifunctional protein that includes general (non sugar- specific) and sugar-specific components of the phosphoenolpyruvate- dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FryABC PTS system is involved in fructose transport.
 
 0.996
ptsA
PEP-protein phosphotransferase system enzyme I; Residues 1 to 711 of 711 are 99.57 pct identical to residues 1 to 711 of 711 from Escherichia coli K-12 Strain MG1655: B3947.
 
 0.992
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.