STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argGArgininosuccinate synthetase; Residues 1 to 447 of 447 are 99.77 pct identical to residues 1 to 447 of 447 from Escherichia coli K-12 Strain MG1655: B3172; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (447 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
 
  
 0.999
argH
Argininosuccinate lyase; Residues 1 to 457 of 457 are 98.68 pct identical to residues 1 to 457 of 457 from Escherichia coli K-12 Strain MG1655: B3960.
 
 
 0.998
argE
Acetylornithine deacetylase; Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde.
  
 0.997
argA
N-acetylglutamate synthase; Residues 1 to 443 of 443 are 100.00 pct identical to residues 1 to 443 of 443 from Escherichia coli K-12 Strain MG1655: B2818; Belongs to the acetyltransferase family. ArgA subfamily.
 
  
 0.988
argC
N-acetyl-gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.986
argI
Ornithine carbamoyltransferase 1; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.979
carB
Carbamoyl-phosphate synthase large subunit; Residues 1 to 1073 of 1073 are 99.72 pct identical to residues 1 to 1073 of 1073 from Escherichia coli K-12 Strain MG1655: B0033.
 
 
 0.974
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.928
asnB
Asparagine synthetase B; Residues 1 to 554 of 554 are 99.45 pct identical to residues 1 to 554 of 554 from Escherichia coli K-12 Strain MG1655: B0674.
   
 0.920
aspC
Aspartate aminotransferase; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B0928.
   
 
 0.913
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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