| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM60174.1 | coaE | NPD11_1401 | NPD11_1017 | tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.664 |
| AQM60174.1 | guaB | NPD11_1401 | NPD11_1506 | tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.426 |
| AQM60174.1 | polA | NPD11_1401 | NPD11_1018 | tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.443 |
| AQM60520.1 | coaE | NPD11_1016 | NPD11_1017 | Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.865 |
| AQM60520.1 | glsA | NPD11_1016 | NPD11_1019 | Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). | Gln_ase: glutaminase A; [E] COG2066 Glutaminase; Belongs to the glutaminase family. | 0.648 |
| AQM60520.1 | polA | NPD11_1016 | NPD11_1018 | Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.804 |
| acpS | coaE | NPD11_2199 | NPD11_1017 | Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.907 |
| coaD | coaE | NPD11_197 | NPD11_1017 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.949 |
| coaD | nadE | NPD11_197 | NPD11_941 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.600 |
| coaE | AQM60174.1 | NPD11_1017 | NPD11_1401 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.664 |
| coaE | AQM60520.1 | NPD11_1017 | NPD11_1016 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). | 0.865 |
| coaE | acpS | NPD11_1017 | NPD11_2199 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.907 |
| coaE | coaD | NPD11_1017 | NPD11_197 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.949 |
| coaE | cobA | NPD11_1017 | NPD11_2831 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; [H] COG0007 Uroporphyrinogen-III methylase. | 0.620 |
| coaE | glsA | NPD11_1017 | NPD11_1019 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Gln_ase: glutaminase A; [E] COG2066 Glutaminase; Belongs to the glutaminase family. | 0.658 |
| coaE | guaB | NPD11_1017 | NPD11_1506 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.675 |
| coaE | hemL | NPD11_1017 | NPD11_2833 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | hemL: glutamate-1-semialdehyde-2,1-aminomutase; [H] COG0001 Glutamate-1-semialdehyde aminotransferase. | 0.591 |
| coaE | nadE | NPD11_1017 | NPD11_941 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.653 |
| coaE | polA | NPD11_1017 | NPD11_1018 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.955 |
| cobA | coaE | NPD11_2831 | NPD11_1017 | cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; [H] COG0007 Uroporphyrinogen-III methylase. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.620 |