STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (270 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folE
folE: GTP cyclohydrolase I; [H] COG0302 GTP cyclohydrolase I.
  
 0.999
pabB
pabB: aminodeoxychorismate synthase, component I; [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
  
 0.957
folC
folC: bifunctional FolC family protein; [H] COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
 0.946
AQM61398.1
HDIG: HDIG domain protein; [R] COG1418 Predicted HD superfamily hydrolase.
 
   
 0.944
AQM60074.1
trpG_papA: glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein; [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II.
 
  
 0.933
AQM59304.1
Aminotransferase class IV family protein; [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
 
  
 0.929
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.886
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.828
AQM60146.1
birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.
  
  
 0.787
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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