Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59281.1 | AQM59735.1 | NPD11_1092 | NPD11_1091 | Vitamin B12 dependent methionine synthase, activation domain protein. | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | 0.975 |
| AQM59281.1 | luxS | NPD11_1092 | NPD11_1093 | Vitamin B12 dependent methionine synthase, activation domain protein. | S-Ribosylhomocysteinase family protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.934 |
| AQM59281.1 | metA | NPD11_1092 | NPD11_2821 | Vitamin B12 dependent methionine synthase, activation domain protein. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.483 |
| AQM59281.1 | metF | NPD11_1092 | NPD11_1094 | Vitamin B12 dependent methionine synthase, activation domain protein. | Fadh2: methylenetetrahydrofolate reductase [NAD(P)H]; [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.974 |
| AQM59281.1 | metK | NPD11_1092 | NPD11_1371 | Vitamin B12 dependent methionine synthase, activation domain protein. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.580 |
| AQM59735.1 | AQM59281.1 | NPD11_1091 | NPD11_1092 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Vitamin B12 dependent methionine synthase, activation domain protein. | 0.975 |
| AQM59735.1 | fhs | NPD11_1091 | NPD11_1714 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.593 |
| AQM59735.1 | folD | NPD11_1091 | NPD11_364 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.582 |
| AQM59735.1 | glyA | NPD11_1091 | NPD11_90 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.467 |
| AQM59735.1 | luxS | NPD11_1091 | NPD11_1093 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | S-Ribosylhomocysteinase family protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.934 |
| AQM59735.1 | metA | NPD11_1091 | NPD11_2821 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.820 |
| AQM59735.1 | metF | NPD11_1091 | NPD11_1094 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Fadh2: methylenetetrahydrofolate reductase [NAD(P)H]; [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.999 |
| AQM59735.1 | metK | NPD11_1091 | NPD11_1371 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.674 |
| AQM59735.1 | nifJ | NPD11_1091 | NPD11_2884 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. | 0.410 |
| AQM59735.1 | thyA | NPD11_1091 | NPD11_2052 | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.411 |
| fhs | AQM59735.1 | NPD11_1714 | NPD11_1091 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | 0.593 |
| fhs | folD | NPD11_1714 | NPD11_364 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.997 |
| fhs | glyA | NPD11_1714 | NPD11_90 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.976 |
| fhs | metF | NPD11_1714 | NPD11_1094 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | Fadh2: methylenetetrahydrofolate reductase [NAD(P)H]; [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.662 |
| folD | AQM59735.1 | NPD11_364 | NPD11_1091 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Pterin binding enzyme family protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | 0.582 |
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