| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NPD11_111 | dapD | NPD11_111 | NPD11_110 | cys/Met metabolism PLP-dependent enzyme family protein; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.599 |
| NPD11_249 | asd | NPD11_249 | NPD11_119 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.993 |
| NPD11_249 | dapA | NPD11_249 | NPD11_118 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.624 |
| NPD11_249 | dapB | NPD11_249 | NPD11_117 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.673 |
| NPD11_249 | dapD | NPD11_249 | NPD11_110 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.600 |
| NPD11_249 | dapF | NPD11_249 | NPD11_387 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.658 |
| NPD11_249 | guaA | NPD11_249 | NPD11_1505 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.480 |
| NPD11_249 | lysA | NPD11_249 | NPD11_2385 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.885 |
| argD | dapD | NPD11_2599 | NPD11_110 | argD: transaminase, acetylornithine/succinylornithine family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.934 |
| argD | guaA | NPD11_2599 | NPD11_1505 | argD: transaminase, acetylornithine/succinylornithine family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.425 |
| asd | NPD11_249 | NPD11_119 | NPD11_249 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.993 |
| asd | dapA | NPD11_119 | NPD11_118 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.996 |
| asd | dapB | NPD11_119 | NPD11_117 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.963 |
| asd | dapD | NPD11_119 | NPD11_110 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.651 |
| asd | dapF | NPD11_119 | NPD11_387 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.787 |
| asd | guaA | NPD11_119 | NPD11_1505 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.643 |
| asd | lysA | NPD11_119 | NPD11_2385 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.688 |
| dapA | NPD11_249 | NPD11_118 | NPD11_249 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.624 |
| dapA | asd | NPD11_118 | NPD11_119 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.996 |
| dapA | dapB | NPD11_118 | NPD11_117 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.998 |