| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59561.1 | dapD | NPD11_1112 | NPD11_110 | Amidohydrolases: amidohydrolase family protein; [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.599 |
| AQM60146.1 | NPD11_249 | NPD11_1072 | NPD11_249 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.494 |
| AQM60146.1 | dapA | NPD11_1072 | NPD11_118 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.431 |
| AQM60146.1 | dapB | NPD11_1072 | NPD11_117 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.730 |
| AQM60146.1 | dapD | NPD11_1072 | NPD11_110 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.617 |
| AQM60146.1 | dapF | NPD11_1072 | NPD11_387 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.487 |
| AQM60146.1 | guaA | NPD11_1072 | NPD11_1505 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.731 |
| AQM60146.1 | lysA | NPD11_1072 | NPD11_2385 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.437 |
| NPD11_249 | AQM60146.1 | NPD11_249 | NPD11_1072 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.494 |
| NPD11_249 | asd | NPD11_249 | NPD11_119 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.989 |
| NPD11_249 | dapA | NPD11_249 | NPD11_118 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.608 |
| NPD11_249 | dapB | NPD11_249 | NPD11_117 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.673 |
| NPD11_249 | dapD | NPD11_249 | NPD11_110 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.674 |
| NPD11_249 | dapF | NPD11_249 | NPD11_387 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.695 |
| NPD11_249 | guaA | NPD11_249 | NPD11_1505 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.546 |
| NPD11_249 | lysA | NPD11_249 | NPD11_2385 | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.887 |
| argD | dapD | NPD11_2599 | NPD11_110 | argD: transaminase, acetylornithine/succinylornithine family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.930 |
| asd | NPD11_249 | NPD11_119 | NPD11_249 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Asp_kinase: aspartate kinase domain protein; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.989 |
| asd | dapA | NPD11_119 | NPD11_118 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.995 |
| asd | dapB | NPD11_119 | NPD11_117 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.931 |