| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59524.1 | AQM61043.1 | NPD11_1113 | NPD11_1114 | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.680 |
| AQM60146.1 | AQM61043.1 | NPD11_1072 | NPD11_1114 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.538 |
| AQM60146.1 | cinA | NPD11_1072 | NPD11_2146 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | pncC_: amidohydrolase, PncC family domain protein; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.455 |
| AQM60146.1 | nadD | NPD11_1072 | NPD11_1294 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.620 |
| AQM60146.1 | nadE | NPD11_1072 | NPD11_941 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.780 |
| AQM60336.1 | AQM61043.1 | NPD11_2483 | NPD11_1114 | Bacterial capsule synthesis PGA_cap family protein; [M] COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation). | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.560 |
| AQM60498.1 | AQM61043.1 | NPD11_2381 | NPD11_1114 | NUDIX domain protein; [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding. | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.913 |
| AQM60498.1 | cinA | NPD11_2381 | NPD11_2146 | NUDIX domain protein; [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding. | pncC_: amidohydrolase, PncC family domain protein; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.913 |
| AQM60498.1 | nadD | NPD11_2381 | NPD11_1294 | NUDIX domain protein; [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.903 |
| AQM60498.1 | nadE | NPD11_2381 | NPD11_941 | NUDIX domain protein; [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.911 |
| AQM60870.1 | AQM61043.1 | NPD11_1747 | NPD11_1114 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.913 |
| AQM60870.1 | deoD | NPD11_1747 | NPD11_699 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | deoD: purine nucleoside phosphorylase; [F] COG0813 Purine-nucleoside phosphorylase. | 0.923 |
| AQM60870.1 | nadE | NPD11_1747 | NPD11_941 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.536 |
| AQM61043.1 | AQM59524.1 | NPD11_1114 | NPD11_1113 | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | 0.680 |
| AQM61043.1 | AQM60146.1 | NPD11_1114 | NPD11_1072 | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.538 |
| AQM61043.1 | AQM60336.1 | NPD11_1114 | NPD11_2483 | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Bacterial capsule synthesis PGA_cap family protein; [M] COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation). | 0.560 |
| AQM61043.1 | AQM60498.1 | NPD11_1114 | NPD11_2381 | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NUDIX domain protein; [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding. | 0.913 |
| AQM61043.1 | AQM60870.1 | NPD11_1114 | NPD11_1747 | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.913 |
| AQM61043.1 | cinA | NPD11_1114 | NPD11_2146 | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | pncC_: amidohydrolase, PncC family domain protein; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.967 |
| AQM61043.1 | deoD | NPD11_1114 | NPD11_699 | Nicotinate phosphoribosyltransferase family protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | deoD: purine nucleoside phosphorylase; [F] COG0813 Purine-nucleoside phosphorylase. | 0.912 |