STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (301 aa)    
Predicted Functional Partners:
thrC
thrC: threonine synthase; [E] COG0498 Threonine synthase.
 
 0.999
NPD11_31
ACT domain protein; [E] COG0460 Homoserine dehydrogenase.
 
 0.991
purM
purM: phosphoribosylformylglycinamidine cyclo-ligase; [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase.
 
    
 0.910
AQM61509.1
[R] COG4492 ACT domain-containing protein; Belongs to the UPF0735 family.
 
     0.865
ilvE
ilvE_II: branched-chain amino acid aminotransferase; [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 
 0.842
sdaAB
Sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit; [E] COG1760 L-serine deaminase.
  
 
 0.838
sdaAA
Sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; [E] COG1760 L-serine deaminase.
  
 
 0.838
cysE
cysE: serine O-acetyltransferase; [E] COG1045 Serine acetyltransferase.
     
 0.831
AQM60991.1
OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein; [E] COG2873 O-acetylhomoserine sulfhydrylase.
    
 0.810
AQM59539.1
C_S_lyase_PatB: C-S lyase family protein; [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
     
  0.800
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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