STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkBpfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (300 aa)    
Predicted Functional Partners:
fruA
fruA: PTS system, fructose subfamily, IIA component domain protein; [G] COG1299 Phosphotransferase system, fructose-specific IIC component.
 
 
 0.999
fruA-2
fruA: PTS system, fructose subfamily, IIA component domain protein; [G] COG1299 Phosphotransferase system, fructose-specific IIC component.
 
 
 0.999
AQM60942.1
deoR-like helix-turn-helix domain protein; [KG] COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.983
fba
Fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II; [G] COG0191 Fructose/tagatose bisphosphate aldolase.
 
 
 0.947
pfp
Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.909
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.908
pfkA1
Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
     
 0.908
AQM60896.1
deoR-like helix-turn-helix domain protein; [KG] COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.757
lacE
lac_pts_IIC: PTS system, lactose-specific IIC component; [G] COG1455 Phosphotransferase system cellobiose-specific component IIC.
  
  
 0.745
AQM59907.1
deoR-like helix-turn-helix domain protein; [KG] COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.715
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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