| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM60204.1 | murA | NPD11_1383 | NPD11_1385 | Peptidase M23 family protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.545 |
| AQM60204.1 | spoIID | NPD11_1383 | NPD11_1384 | Peptidase M23 family protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | 0.736 |
| AQM60204.1 | spoIIID | NPD11_1383 | NPD11_1382 | Peptidase M23 family protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.679 |
| murA | AQM60204.1 | NPD11_1385 | NPD11_1383 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Peptidase M23 family protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | 0.545 |
| murA | spoIID | NPD11_1385 | NPD11_1384 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | 0.673 |
| murA | spoIIID | NPD11_1385 | NPD11_1382 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.496 |
| spoIIAB | spoIID | NPD11_2916 | NPD11_1384 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | 0.757 |
| spoIIAB | spoIIE | NPD11_2916 | NPD11_1718 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_II_E: stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit. | 0.913 |
| spoIIAB | spoIIIAA | NPD11_2916 | NPD11_374 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_III_AA: stage III sporulation protein AA; [S] COG3854 Uncharacterized protein conserved in bacteria. | 0.789 |
| spoIIAB | spoIIID | NPD11_2916 | NPD11_1382 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.877 |
| spoIIAB | spoIIM | NPD11_2916 | NPD11_351 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spo_II_M: stage II sporulation protein M; [S] COG1300 Uncharacterized membrane protein. | 0.599 |
| spoIIAB | spoIIP | NPD11_2916 | NPD11_2926 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_II_P: stage II sporulation P family protein. | 0.898 |
| spoIIAB | spoIIR | NPD11_2916 | NPD11_1413 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_II_R: stage II sporulation protein R. | 0.898 |
| spoIIAB | spoIVA | NPD11_2916 | NPD11_172 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.846 |
| spoIID | AQM60204.1 | NPD11_1384 | NPD11_1383 | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | Peptidase M23 family protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | 0.736 |
| spoIID | murA | NPD11_1384 | NPD11_1385 | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.673 |
| spoIID | spoIIAB | NPD11_1384 | NPD11_2916 | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.757 |
| spoIID | spoIIE | NPD11_1384 | NPD11_1718 | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | spore_II_E: stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit. | 0.730 |
| spoIID | spoIIIAA | NPD11_1384 | NPD11_374 | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | spore_III_AA: stage III sporulation protein AA; [S] COG3854 Uncharacterized protein conserved in bacteria. | 0.693 |
| spoIID | spoIIID | NPD11_1384 | NPD11_1382 | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.828 |