| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59946.1 | NPD11_148 | NPD11_2068 | NPD11_148 | Aminotransferase class-V family protein; [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | 0.559 |
| NPD11_146 | NPD11_148 | NPD11_146 | NPD11_148 | Tetratricopeptide repeat family protein; [R] COG0457 FOG: TPR repeat. | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | 0.552 |
| NPD11_146 | noxC | NPD11_146 | NPD11_147 | Tetratricopeptide repeat family protein; [R] COG0457 FOG: TPR repeat. | Nitroreductase family protein; [C] COG0778 Nitroreductase. | 0.601 |
| NPD11_148 | AQM59946.1 | NPD11_148 | NPD11_2068 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | Aminotransferase class-V family protein; [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. | 0.559 |
| NPD11_148 | NPD11_146 | NPD11_148 | NPD11_146 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | Tetratricopeptide repeat family protein; [R] COG0457 FOG: TPR repeat. | 0.552 |
| NPD11_148 | fhs | NPD11_148 | NPD11_1714 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.975 |
| NPD11_148 | fmt | NPD11_148 | NPD11_183 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.914 |
| NPD11_148 | folD | NPD11_148 | NPD11_364 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.968 |
| NPD11_148 | noxC | NPD11_148 | NPD11_147 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | Nitroreductase family protein; [C] COG0778 Nitroreductase. | 0.709 |
| NPD11_148 | phnW | NPD11_148 | NPD11_2312 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | 2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. | 0.483 |
| NPD11_148 | prmC | NPD11_148 | NPD11_1404 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.493 |
| NPD11_148 | purH | NPD11_148 | NPD11_905 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.906 |
| NPD11_148 | purN | NPD11_148 | NPD11_906 | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.909 |
| fhs | NPD11_148 | NPD11_1714 | NPD11_148 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | 0.975 |
| fhs | fmt | NPD11_1714 | NPD11_183 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.497 |
| fhs | folD | NPD11_1714 | NPD11_364 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.997 |
| fhs | purH | NPD11_1714 | NPD11_905 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.980 |
| fhs | purN | NPD11_1714 | NPD11_906 | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.969 |
| fmt | NPD11_148 | NPD11_183 | NPD11_148 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Formiminotransferase-cyclodeaminase family protein; [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase. | 0.914 |
| fmt | fhs | NPD11_183 | NPD11_1714 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Formate--tetrahydrofolate ligase family protein; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.497 |