Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
sepFHypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (156 aa)    
Predicted Functional Partners:
NPD11_165
YGGT family protein; [S] COG0762 Predicted integral membrane protein.
  
  
 0.981
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.955
NPD11_163
Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.954
NPD11_166
S4 domain protein; [S] COG2302 Uncharacterized conserved protein, contains S4-like domain.
 
  
 0.944
NPD11_167
divI1A_: DivIVA domain protein; [D] COG3599 Cell division initiation protein.
  
  
 0.937
NPD11_465
Cell division FtsA family protein; [D] COG0849 Actin-like ATPase involved in cell division.
  
 
 0.806
NPD11_159
POTRA domain, FtsQ-type family protein; Essential cell division protein.
  
  
 0.768
NPD11_162
Conserved hypothetical protein; [S] COG3879 Uncharacterized protein conserved in bacteria.
 
   
 0.746
NPD11_160
Conserved hypothetical protein; [S] COG3879 Uncharacterized protein conserved in bacteria.
 
   
 0.731
NPD11_161
Conserved hypothetical protein; [S] COG3856 Uncharacterized conserved protein (small basic protein).
 
     0.720
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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