| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59583.1 | AQM60106.1 | NPD11_1665 | NPD11_1666 | yacP-like NYN domain protein; [R] COG3688 Predicted RNA-binding protein containing a PIN domain. | RNA 2'-O ribose methyltransferase substrate binding family protein; [J] COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.945 |
| AQM59583.1 | NPD11_166 | NPD11_1665 | NPD11_166 | yacP-like NYN domain protein; [R] COG3688 Predicted RNA-binding protein containing a PIN domain. | S4 domain protein; [S] COG2302 Uncharacterized conserved protein, contains S4-like domain. | 0.446 |
| AQM59583.1 | cysS | NPD11_1665 | NPD11_1668 | yacP-like NYN domain protein; [R] COG3688 Predicted RNA-binding protein containing a PIN domain. | cysS: cysteine--tRNA ligase; [J] COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.882 |
| AQM59583.1 | mrnC | NPD11_1665 | NPD11_1667 | yacP-like NYN domain protein; [R] COG3688 Predicted RNA-binding protein containing a PIN domain. | Ribonuclease III domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.947 |
| AQM59583.1 | proS | NPD11_1665 | NPD11_1669 | yacP-like NYN domain protein; [R] COG3688 Predicted RNA-binding protein containing a PIN domain. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.584 |
| AQM59583.1 | sigH | NPD11_1665 | NPD11_1664 | yacP-like NYN domain protein; [R] COG3688 Predicted RNA-binding protein containing a PIN domain. | spore_sigH: RNA polymerase sigma-H factor; [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. | 0.802 |
| AQM60106.1 | AQM59583.1 | NPD11_1666 | NPD11_1665 | RNA 2'-O ribose methyltransferase substrate binding family protein; [J] COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | yacP-like NYN domain protein; [R] COG3688 Predicted RNA-binding protein containing a PIN domain. | 0.945 |
| AQM60106.1 | cysS | NPD11_1666 | NPD11_1668 | RNA 2'-O ribose methyltransferase substrate binding family protein; [J] COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | cysS: cysteine--tRNA ligase; [J] COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.891 |
| AQM60106.1 | mrnC | NPD11_1666 | NPD11_1667 | RNA 2'-O ribose methyltransferase substrate binding family protein; [J] COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribonuclease III domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.937 |
| AQM60106.1 | proS | NPD11_1666 | NPD11_1669 | RNA 2'-O ribose methyltransferase substrate binding family protein; [J] COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.672 |
| AQM60106.1 | rplC | NPD11_1666 | NPD11_1648 | RNA 2'-O ribose methyltransferase substrate binding family protein; [J] COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.675 |
| AQM60106.1 | sigH | NPD11_1666 | NPD11_1664 | RNA 2'-O ribose methyltransferase substrate binding family protein; [J] COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | spore_sigH: RNA polymerase sigma-H factor; [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. | 0.717 |
| AQM60651.1 | NPD11_166 | NPD11_1293 | NPD11_166 | HD domain protein; [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism. | S4 domain protein; [S] COG2302 Uncharacterized conserved protein, contains S4-like domain. | 0.485 |
| AQM60651.1 | mrnC | NPD11_1293 | NPD11_1667 | HD domain protein; [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism. | Ribonuclease III domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.624 |
| AQM60651.1 | polC | NPD11_1293 | NPD11_235 | HD domain protein; [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism. | DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.640 |
| NPD11_166 | AQM59583.1 | NPD11_166 | NPD11_1665 | S4 domain protein; [S] COG2302 Uncharacterized conserved protein, contains S4-like domain. | yacP-like NYN domain protein; [R] COG3688 Predicted RNA-binding protein containing a PIN domain. | 0.446 |
| NPD11_166 | AQM60651.1 | NPD11_166 | NPD11_1293 | S4 domain protein; [S] COG2302 Uncharacterized conserved protein, contains S4-like domain. | HD domain protein; [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism. | 0.485 |
| NPD11_166 | NPD11_388 | NPD11_166 | NPD11_388 | S4 domain protein; [S] COG2302 Uncharacterized conserved protein, contains S4-like domain. | [K] COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP. | 0.448 |
| NPD11_166 | mrnC | NPD11_166 | NPD11_1667 | S4 domain protein; [S] COG2302 Uncharacterized conserved protein, contains S4-like domain. | Ribonuclease III domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.754 |
| NPD11_166 | polC | NPD11_166 | NPD11_235 | S4 domain protein; [S] COG2302 Uncharacterized conserved protein, contains S4-like domain. | DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.435 |