| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| spo0A | spoIIAB | NPD11_354 | NPD11_2916 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.866 |
| spo0A | spoIID | NPD11_354 | NPD11_1384 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | 0.540 |
| spo0A | spoIIIAA | NPD11_354 | NPD11_374 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_III_AA: stage III sporulation protein AA; [S] COG3854 Uncharacterized protein conserved in bacteria. | 0.832 |
| spo0A | spoIIIAD | NPD11_354 | NPD11_371 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_III_AD: stage III sporulation protein AD. | 0.842 |
| spo0A | spoIIIAG | NPD11_354 | NPD11_368 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_III_AG: stage III sporulation protein AG. | 0.820 |
| spo0A | spoIIID | NPD11_354 | NPD11_1382 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.862 |
| spo0A | spoIIP | NPD11_354 | NPD11_2926 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_II_P: stage II sporulation P family protein. | 0.783 |
| spo0A | spoIIR | NPD11_354 | NPD11_1413 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_II_R: stage II sporulation protein R. | 0.836 |
| spo0A | spoIVA | NPD11_354 | NPD11_172 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.856 |
| spo0A | ylbJ | NPD11_354 | NPD11_198 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_ylbJ: sporulation integral membrane protein YlbJ; [S] COG3314 Uncharacterized protein conserved in bacteria. | 0.730 |
| spoIIAB | spo0A | NPD11_2916 | NPD11_354 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.866 |
| spoIIAB | spoIID | NPD11_2916 | NPD11_1384 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | 0.737 |
| spoIIAB | spoIIIAA | NPD11_2916 | NPD11_374 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_III_AA: stage III sporulation protein AA; [S] COG3854 Uncharacterized protein conserved in bacteria. | 0.796 |
| spoIIAB | spoIIIAD | NPD11_2916 | NPD11_371 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_III_AD: stage III sporulation protein AD. | 0.752 |
| spoIIAB | spoIIIAG | NPD11_2916 | NPD11_368 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_III_AG: stage III sporulation protein AG. | 0.758 |
| spoIIAB | spoIIID | NPD11_2916 | NPD11_1382 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.863 |
| spoIIAB | spoIIP | NPD11_2916 | NPD11_2926 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_II_P: stage II sporulation P family protein. | 0.865 |
| spoIIAB | spoIIR | NPD11_2916 | NPD11_1413 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_II_R: stage II sporulation protein R. | 0.871 |
| spoIIAB | spoIVA | NPD11_2916 | NPD11_172 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.837 |
| spoIIAB | ylbJ | NPD11_2916 | NPD11_198 | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | spore_ylbJ: sporulation integral membrane protein YlbJ; [S] COG3314 Uncharacterized protein conserved in bacteria. | 0.770 |
