| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gpr | sigE | NPD11_2925 | NPD11_461 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.769 |
| gpr | sigG | NPD11_2925 | NPD11_460 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.770 |
| gpr | spo0A | NPD11_2925 | NPD11_354 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.838 |
| gpr | spoIIAB | NPD11_2925 | NPD11_2916 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.830 |
| gpr | spoIIE | NPD11_2925 | NPD11_1718 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_II_E: stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit. | 0.770 |
| gpr | spoIIIAA | NPD11_2925 | NPD11_374 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_III_AA: stage III sporulation protein AA; [S] COG3854 Uncharacterized protein conserved in bacteria. | 0.753 |
| gpr | spoIIID | NPD11_2925 | NPD11_1382 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.771 |
| gpr | spoIIR | NPD11_2925 | NPD11_1413 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_II_R: stage II sporulation protein R. | 0.770 |
| gpr | spoVAD | NPD11_2925 | NPD11_2920 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_V_AD: stage V sporulation protein AD. | 0.921 |
| gpr | spoVT | NPD11_2925 | NPD11_1734 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_V_T: stage V sporulation protein T; [K] COG2002 Regulators of stationary/sporulation gene expression. | 0.796 |
| sigE | gpr | NPD11_461 | NPD11_2925 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.769 |
| sigE | sigG | NPD11_461 | NPD11_460 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.759 |
| sigE | spo0A | NPD11_461 | NPD11_354 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.846 |
| sigE | spoIIAB | NPD11_461 | NPD11_2916 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.771 |
| sigE | spoIIE | NPD11_461 | NPD11_1718 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_II_E: stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit. | 0.766 |
| sigE | spoIIIAA | NPD11_461 | NPD11_374 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_III_AA: stage III sporulation protein AA; [S] COG3854 Uncharacterized protein conserved in bacteria. | 0.761 |
| sigE | spoIIID | NPD11_461 | NPD11_1382 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.794 |
| sigE | spoIIR | NPD11_461 | NPD11_1413 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_II_R: stage II sporulation protein R. | 0.799 |
| sigE | spoVAD | NPD11_461 | NPD11_2920 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_V_AD: stage V sporulation protein AD. | 0.773 |
| sigE | spoVT | NPD11_461 | NPD11_1734 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_V_T: stage V sporulation protein T; [K] COG2002 Regulators of stationary/sporulation gene expression. | 0.795 |
STRING v12.5 is now available!
