node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NPD11_176 | NPD11_177 | NPD11_176 | NPD11_177 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | 0.916 |
NPD11_176 | NPD11_184 | NPD11_176 | NPD11_184 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | Neutral zinc metallopeptidase family protein; [R] COG2738 Predicted Zn-dependent protease. | 0.628 |
NPD11_176 | coaBC | NPD11_176 | NPD11_180 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.814 |
NPD11_176 | def | NPD11_176 | NPD11_182 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.691 |
NPD11_176 | fmt | NPD11_176 | NPD11_183 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.666 |
NPD11_176 | gmk | NPD11_176 | NPD11_178 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.905 |
NPD11_176 | priA | NPD11_176 | NPD11_181 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.712 |
NPD11_176 | rlmN | NPD11_176 | NPD11_186 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | 23S rRNA (adenine(2503)-C(2))-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.615 |
NPD11_176 | rpoZ | NPD11_176 | NPD11_179 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.876 |
NPD11_176 | rsmB | NPD11_176 | NPD11_185 | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.722 |
NPD11_177 | NPD11_176 | NPD11_177 | NPD11_176 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | Conserved hypothetical protein; [S] COG1561 Uncharacterized stress-induced protein. | 0.916 |
NPD11_177 | NPD11_184 | NPD11_177 | NPD11_184 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | Neutral zinc metallopeptidase family protein; [R] COG2738 Predicted Zn-dependent protease. | 0.643 |
NPD11_177 | coaBC | NPD11_177 | NPD11_180 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.836 |
NPD11_177 | def | NPD11_177 | NPD11_182 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.718 |
NPD11_177 | fmt | NPD11_177 | NPD11_183 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.676 |
NPD11_177 | gmk | NPD11_177 | NPD11_178 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.953 |
NPD11_177 | priA | NPD11_177 | NPD11_181 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.724 |
NPD11_177 | rlmN | NPD11_177 | NPD11_186 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | 23S rRNA (adenine(2503)-C(2))-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.621 |
NPD11_177 | rpoZ | NPD11_177 | NPD11_179 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.858 |
NPD11_177 | rsmB | NPD11_177 | NPD11_185 | Conserved hypothetical protein; [S] COG2052 Uncharacterized protein conserved in bacteria; Belongs to the RemA family. | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.683 |