sbcD protein (Clostridium baratii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

sbcD

Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (399 aa)

Predicted Functional Partners:

polA

0.999

AQM59931.1

0.997

NPD11_416

0.867

addA

0.721

recA

0.698

recQ

0.658

recQ-2

0.638

AQM58789.1

0.628

AQM59451.1

0.609

addB

0.608

Your Current Organism:

Clostridium baratii

NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQM58789.1	polA	NPD11_2193	NPD11_1018	DEAD_2 family protein; [KL] COG1199 Rad3-related DNA helicases.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.919
AQM58789.1	recA	NPD11_2193	NPD11_254	DEAD_2 family protein; [KL] COG1199 Rad3-related DNA helicases.	Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.453
AQM58789.1	sbcD	NPD11_2193	NPD11_1878	DEAD_2 family protein; [KL] COG1199 Rad3-related DNA helicases.	Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.	0.628
AQM59451.1	sbcD	NPD11_2102	NPD11_1878	[P] COG0659 Sulfate permease and related transporters (MFS superfamily).	Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.	0.609
AQM59931.1	addA	NPD11_1877	NPD11_1883	AAA domain protein; [L] COG0419 ATPase involved in DNA repair.	Helicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase.	0.638
AQM59931.1	addB	NPD11_1877	NPD11_1884	AAA domain protein; [L] COG0419 ATPase involved in DNA repair.	Helicase-exonuclease AddAB, AddB subunit; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily.	0.513
AQM59931.1	polA	NPD11_1877	NPD11_1018	AAA domain protein; [L] COG0419 ATPase involved in DNA repair.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.999
AQM59931.1	recA	NPD11_1877	NPD11_254	AAA domain protein; [L] COG0419 ATPase involved in DNA repair.	Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.504
AQM59931.1	recQ	NPD11_1877	NPD11_1150	AAA domain protein; [L] COG0419 ATPase involved in DNA repair.	recQ: ATP-dependent DNA helicase RecQ; [L] COG0514 Superfamily II DNA helicase.	0.589
AQM59931.1	recQ-2	NPD11_1877	NPD11_2631	AAA domain protein; [L] COG0419 ATPase involved in DNA repair.	recQ: ATP-dependent DNA helicase RecQ; [L] COG0514 Superfamily II DNA helicase.	0.565
AQM59931.1	sbcD	NPD11_1877	NPD11_1878	AAA domain protein; [L] COG0419 ATPase involved in DNA repair.	Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.	0.997
NPD11_416	polA	NPD11_416	NPD11_1018	Phage tail tape measure, family, core region domain protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.999
NPD11_416	recA	NPD11_416	NPD11_254	Phage tail tape measure, family, core region domain protein.	Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.548
NPD11_416	recQ	NPD11_416	NPD11_1150	Phage tail tape measure, family, core region domain protein.	recQ: ATP-dependent DNA helicase RecQ; [L] COG0514 Superfamily II DNA helicase.	0.562
NPD11_416	recQ-2	NPD11_416	NPD11_2631	Phage tail tape measure, family, core region domain protein.	recQ: ATP-dependent DNA helicase RecQ; [L] COG0514 Superfamily II DNA helicase.	0.562
NPD11_416	sbcD	NPD11_416	NPD11_1878	Phage tail tape measure, family, core region domain protein.	Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.	0.867
addA	AQM59931.1	NPD11_1883	NPD11_1877	Helicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase.	AAA domain protein; [L] COG0419 ATPase involved in DNA repair.	0.638
addA	addB	NPD11_1883	NPD11_1884	Helicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase.	Helicase-exonuclease AddAB, AddB subunit; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily.	0.999
addA	polA	NPD11_1883	NPD11_1018	Helicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.685
addA	recA	NPD11_1883	NPD11_254	Helicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase.	Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.564

page 1 of 3

Server load: low (30%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About