| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM58700.1 | dnaB | NPD11_1958 | NPD11_1934 | istB-like ATP binding family protein; [L] COG1484 DNA replication protein. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.843 |
| AQM58700.1 | polA | NPD11_1958 | NPD11_1018 | istB-like ATP binding family protein; [L] COG1484 DNA replication protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.677 |
| AQM60557.1 | AQM61049.1 | NPD11_1931 | NPD11_1930 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | mazG-like family protein. | 0.791 |
| AQM60557.1 | dnaB | NPD11_1931 | NPD11_1934 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.675 |
| AQM60557.1 | lonC | NPD11_1931 | NPD11_1933 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | spore_lon_C: ATP-dependent protease, Lon family; [O] COG1067 Predicted ATP-dependent protease. | 0.818 |
| AQM60557.1 | rplI | NPD11_1931 | NPD11_1932 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.866 |
| AQM60557.1 | ssb | NPD11_1931 | NPD11_1928 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Ssb: single-stranded DNA-binding family protein; [L] COG0629 Single-stranded DNA-binding protein. | 0.592 |
| AQM61049.1 | AQM60557.1 | NPD11_1930 | NPD11_1931 | mazG-like family protein. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.791 |
| AQM61049.1 | dnaB | NPD11_1930 | NPD11_1934 | mazG-like family protein. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.616 |
| AQM61049.1 | lonC | NPD11_1930 | NPD11_1933 | mazG-like family protein. | spore_lon_C: ATP-dependent protease, Lon family; [O] COG1067 Predicted ATP-dependent protease. | 0.775 |
| AQM61049.1 | rplI | NPD11_1930 | NPD11_1932 | mazG-like family protein. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.791 |
| AQM61049.1 | ssb | NPD11_1930 | NPD11_1928 | mazG-like family protein. | Ssb: single-stranded DNA-binding family protein; [L] COG0629 Single-stranded DNA-binding protein. | 0.614 |
| dnaA | dnaB | NPD11_1908 | NPD11_1934 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.648 |
| dnaA | dnaG | NPD11_1908 | NPD11_2954 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.564 |
| dnaA | polA | NPD11_1908 | NPD11_1018 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.574 |
| dnaB | AQM58700.1 | NPD11_1934 | NPD11_1958 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | istB-like ATP binding family protein; [L] COG1484 DNA replication protein. | 0.843 |
| dnaB | AQM60557.1 | NPD11_1934 | NPD11_1931 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.675 |
| dnaB | AQM61049.1 | NPD11_1934 | NPD11_1930 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | mazG-like family protein. | 0.616 |
| dnaB | dnaA | NPD11_1934 | NPD11_1908 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.648 |
| dnaB | dnaG | NPD11_1934 | NPD11_2954 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.955 |