| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM61380.1 | NPD11_21 | NPD11_2585 | NPD11_21 | CM_mono_grmpos: chorismate mutase; [E] COG0077 Prephenate dehydratase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.580 |
| AQM61380.1 | dtd | NPD11_2585 | NPD11_22 | CM_mono_grmpos: chorismate mutase; [E] COG0077 Prephenate dehydratase. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.449 |
| NPD11_19 | NPD11_21 | NPD11_19 | NPD11_21 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.592 |
| NPD11_19 | NPD11_23 | NPD11_19 | NPD11_23 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | Beta-lactamase superfamily domain protein; [R] COG0491 Zn-dependent hydrolases, including glyoxylases. | 0.567 |
| NPD11_19 | apt | NPD11_19 | NPD11_20 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.716 |
| NPD11_19 | aspS | NPD11_19 | NPD11_26 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.512 |
| NPD11_19 | dtd | NPD11_19 | NPD11_22 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.570 |
| NPD11_19 | hemZ | NPD11_19 | NPD11_24 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ; [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases. | 0.553 |
| NPD11_19 | hisS | NPD11_19 | NPD11_25 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | hisS: histidine--tRNA ligase; [J] COG0124 Histidyl-tRNA synthetase. | 0.467 |
| NPD11_19 | secD | NPD11_19 | NPD11_17 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.662 |
| NPD11_19 | secF | NPD11_19 | NPD11_18 | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.653 |
| NPD11_21 | AQM61380.1 | NPD11_21 | NPD11_2585 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | CM_mono_grmpos: chorismate mutase; [E] COG0077 Prephenate dehydratase. | 0.580 |
| NPD11_21 | NPD11_19 | NPD11_21 | NPD11_19 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative single-stranded-DNA-specific exonuclease recJ; [L] COG0608 Single-stranded DNA-specific exonuclease. | 0.592 |
| NPD11_21 | NPD11_23 | NPD11_21 | NPD11_23 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Beta-lactamase superfamily domain protein; [R] COG0491 Zn-dependent hydrolases, including glyoxylases. | 0.780 |
| NPD11_21 | apt | NPD11_21 | NPD11_20 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.685 |
| NPD11_21 | aspS | NPD11_21 | NPD11_26 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.683 |
| NPD11_21 | dtd | NPD11_21 | NPD11_22 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.891 |
| NPD11_21 | hemZ | NPD11_21 | NPD11_24 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ; [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases. | 0.773 |
| NPD11_21 | hisS | NPD11_21 | NPD11_25 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | hisS: histidine--tRNA ligase; [J] COG0124 Histidyl-tRNA synthetase. | 0.742 |
| NPD11_21 | secD | NPD11_21 | NPD11_17 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.527 |