| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59524.1 | mutL | NPD11_1113 | NPD11_304 | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.612 |
| AQM59524.1 | pcrA | NPD11_1113 | NPD11_1489 | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | pcrA: ATP-dependent DNA helicase PcrA; [L] COG0210 Superfamily I DNA and RNA helicases. | 0.923 |
| AQM59524.1 | polA | NPD11_1113 | NPD11_1018 | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.683 |
| AQM59524.1 | recA | NPD11_1113 | NPD11_254 | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.717 |
| AQM59524.1 | uvrA | NPD11_1113 | NPD11_2218 | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.498 |
| AQM59524.1 | uvrB | NPD11_1113 | NPD11_2211 | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.742 |
| AQM59524.1 | uvrC | NPD11_1113 | NPD11_2222 | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.692 |
| AQM60909.1 | pheT | NPD11_2210 | NPD11_137 | Hypothetical protein; Prc: C-terminal processing peptidase family protein; [M] COG0793 Periplasmic protease; Belongs to the peptidase S41A family. | pheT_bact: phenylalanine--tRNA ligase, beta subunit; [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.508 |
| AQM60909.1 | uvrA | NPD11_2210 | NPD11_2218 | Hypothetical protein; Prc: C-terminal processing peptidase family protein; [M] COG0793 Periplasmic protease; Belongs to the peptidase S41A family. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.403 |
| AQM60909.1 | uvrB | NPD11_2210 | NPD11_2211 | Hypothetical protein; Prc: C-terminal processing peptidase family protein; [M] COG0793 Periplasmic protease; Belongs to the peptidase S41A family. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.698 |
| dnaK | mutL | NPD11_2933 | NPD11_304 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.499 |
| dnaK | pheT | NPD11_2933 | NPD11_137 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | pheT_bact: phenylalanine--tRNA ligase, beta subunit; [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.443 |
| dnaK | polA | NPD11_2933 | NPD11_1018 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.631 |
| dnaK | recA | NPD11_2933 | NPD11_254 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.574 |
| dnaK | uvrA | NPD11_2933 | NPD11_2218 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.603 |
| dnaK | uvrB | NPD11_2933 | NPD11_2211 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.698 |
| mutL | AQM59524.1 | NPD11_304 | NPD11_1113 | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. | 0.612 |
| mutL | dnaK | NPD11_304 | NPD11_2933 | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.499 |
| mutL | pcrA | NPD11_304 | NPD11_1489 | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | pcrA: ATP-dependent DNA helicase PcrA; [L] COG0210 Superfamily I DNA and RNA helicases. | 0.633 |
| mutL | pheT | NPD11_304 | NPD11_137 | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | pheT_bact: phenylalanine--tRNA ligase, beta subunit; [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.564 |
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