STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dprAdprA: DNA protecting protein DprA; [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. (352 aa)    
Predicted Functional Partners:
NPD11_221
Sigma-54 interaction domain protein; [O] COG0606 Predicted ATPase with chaperone activity.
 
 0.962
NPD11_220
Conserved hypothetical protein; [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
 
    0.871
AQM60286.1
[R] COG1040 Predicted amidophosphoribosyltransferases.
 
 
 0.870
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.869
AQM61379.1
Hypothetical protein; comEC_N-term: ComEC/Rec2-related domain protein; [R] COG0658 Predicted membrane metal-binding protein.
 
  
 0.769
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
 
 0.690
AQM61199.1
Type IV leader peptidase family protein; [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.
  
  
 0.585
NPD11_712
Type IV leader peptidase family protein; [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.
  
  
 0.585
codY
GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
     
 0.570
AQM59365.1
Radc: DNA repair RadC family protein; [L] COG2003 DNA repair proteins; Belongs to the UPF0758 family.
  
  
 0.566
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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