STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clsCardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (511 aa)    
Predicted Functional Partners:
cls-2
Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  
  
 
0.919
AQM60391.1
Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.583
AQM60018.1
trkA-C domain protein.
       0.492
nifU
nifU_clost: FeS cluster assembly scaffold protein NifU; [C] COG0822 NifU homolog involved in Fe-S cluster formation.
   
 
 0.483
AQM60183.1
nifU-like N terminal domain protein; [C] COG0822 NifU homolog involved in Fe-S cluster formation.
   
 
 0.478
NPD11_100
coA_E_activ: putative CoA-substrate-specific enzyme activase domain protein; [I] COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain).
  
    0.458
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
   
 0.435
phnX
Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.
  
   0.413
AQM61290.1
ROK family protein; [KG] COG1940 Transcriptional regulator/sugar kinase.
       0.406
AQM60399.1
Membrane domain of glycerophosphoryl diester phosphodiesterase family protein; [C] COG0584 Glycerophosphoryl diester phosphodiesterase.
     
 0.406
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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