Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spoVS[S] COG2359 Uncharacterized protein conserved in bacteria. (86 aa)    
Predicted Functional Partners:
rny
Ribonuclease Y; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
       0.646
ptsH
Phosphocarrier protein HPr; [G] COG1925 Phosphotransferase system, HPr-related proteins.
  
    0.606
spoIIM
spo_II_M: stage II sporulation protein M; [S] COG1300 Uncharacterized membrane protein.
  
   
 0.486
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
       0.469
NPD11_184
Neutral zinc metallopeptidase family protein; [R] COG2738 Predicted Zn-dependent protease.
 
     0.456
spoVG
spoVG family protein; Could be involved in septation.
      
 0.428
yabP
spore_yabP: sporulation protein YabP.
  
   
 0.426
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
      
 0.416
spoIIIAC
spore_III_AC: stage III sporulation protein AC.
      
 0.401
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
Server load: high (96%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.