| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59780.1 | AQM60280.1 | NPD11_2574 | NPD11_2575 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | Putative zinc-binding domain protein. | 0.451 |
| AQM59780.1 | AQM60941.1 | NPD11_2574 | NPD11_2710 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | 0.428 |
| AQM59780.1 | dnaN | NPD11_2574 | NPD11_1907 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.780 |
| AQM59780.1 | lysS | NPD11_2574 | NPD11_1710 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | lysS_bact: lysine--tRNA ligase; [J] COG1190 Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.480 |
| AQM59780.1 | mutL | NPD11_2574 | NPD11_304 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.940 |
| AQM59780.1 | mutS2 | NPD11_2574 | NPD11_141 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | 0.428 |
| AQM59780.1 | plc | NPD11_2574 | NPD11_1525 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | Phospholipase C. | 0.473 |
| AQM59780.1 | polA | NPD11_2574 | NPD11_1018 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.816 |
| AQM59780.1 | rbr3A-2 | NPD11_2574 | NPD11_2573 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | Reverse rubrerythrin-1; [C] COG1592 Rubrerythrin. | 0.504 |
| AQM59780.1 | topA | NPD11_2574 | NPD11_223 | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.537 |
| AQM60280.1 | AQM59780.1 | NPD11_2575 | NPD11_2574 | Putative zinc-binding domain protein. | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | 0.451 |
| AQM60941.1 | AQM59780.1 | NPD11_2710 | NPD11_2574 | BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | 0.428 |
| AQM60941.1 | dnaN | NPD11_2710 | NPD11_1907 | BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.973 |
| AQM60941.1 | mutL | NPD11_2710 | NPD11_304 | BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.465 |
| AQM60941.1 | mutS2 | NPD11_2710 | NPD11_141 | BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | 0.453 |
| AQM60941.1 | polA | NPD11_2710 | NPD11_1018 | BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.800 |
| AQM60941.1 | topA | NPD11_2710 | NPD11_223 | BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.819 |
| dnaN | AQM59780.1 | NPD11_1907 | NPD11_2574 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | mutS domain V family protein; [L] COG0249 Mismatch repair ATPase (MutS family). | 0.780 |
| dnaN | AQM60941.1 | NPD11_1907 | NPD11_2710 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. | 0.973 |
| dnaN | mutL | NPD11_1907 | NPD11_304 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.964 |