STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (205 aa)    
Predicted Functional Partners:
thiD
HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 0.999
thiM
Hydroxyethylthiazole kinase family protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
 
 0.999
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
 0.909
tenA
Thiaminase II; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
  
 0.898
AQM60077.1
Conserved hypothetical protein; [S] COG4732 Predicted membrane protein.
 
     0.864
hydG-2
rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
 
  
 0.747
hydG
rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
  
  
 0.714
AQM59427.1
HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein; [R] COG0637 Predicted phosphatase/phosphohexomutase.
      0.632
AQM59690.1
Hypothetical protein.
       0.598
NPD11_279
Rhodanese-like domain protein; [P] COG0607 Rhodanese-related sulfurtransferase.
     
 0.569
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.