| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM60146.1 | bioD | NPD11_1072 | NPD11_573 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.774 |
| AQM60146.1 | folB | NPD11_1072 | NPD11_1055 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.787 |
| AQM60146.1 | hydE | NPD11_1072 | NPD11_2808 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE; [H] COG0502 Biotin synthase and related enzymes. | 0.769 |
| AQM60146.1 | nadE | NPD11_1072 | NPD11_941 | birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.780 |
| AQM60523.1 | AQM60659.1 | NPD11_2807 | NPD11_2164 | Hypothetical protein. | Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | 0.413 |
| AQM60523.1 | AQM60963.1 | NPD11_2807 | NPD11_1861 | Hypothetical protein. | [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | 0.533 |
| AQM60523.1 | hydE | NPD11_2807 | NPD11_2808 | Hypothetical protein. | rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE; [H] COG0502 Biotin synthase and related enzymes. | 0.958 |
| AQM60523.1 | hydF | NPD11_2807 | NPD11_2811 | Hypothetical protein. | GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF; [R] COG1160 Predicted GTPases. | 0.935 |
| AQM60523.1 | hydG | NPD11_2807 | NPD11_2809 | Hypothetical protein. | rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. | 0.904 |
| AQM60523.1 | hydG-2 | NPD11_2807 | NPD11_2810 | Hypothetical protein. | rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. | 0.884 |
| AQM60659.1 | AQM60523.1 | NPD11_2164 | NPD11_2807 | Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | Hypothetical protein. | 0.413 |
| AQM60659.1 | AQM60963.1 | NPD11_2164 | NPD11_1861 | Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | 0.402 |
| AQM60659.1 | hydE | NPD11_2164 | NPD11_2808 | Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE; [H] COG0502 Biotin synthase and related enzymes. | 0.684 |
| AQM60659.1 | hydF | NPD11_2164 | NPD11_2811 | Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF; [R] COG1160 Predicted GTPases. | 0.720 |
| AQM60659.1 | hydG | NPD11_2164 | NPD11_2809 | Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. | 0.660 |
| AQM60659.1 | hydG-2 | NPD11_2164 | NPD11_2810 | Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. | 0.655 |
| AQM60963.1 | AQM60523.1 | NPD11_1861 | NPD11_2807 | [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | Hypothetical protein. | 0.533 |
| AQM60963.1 | AQM60659.1 | NPD11_1861 | NPD11_2164 | [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | 0.402 |
| AQM60963.1 | hydE | NPD11_1861 | NPD11_2808 | [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE; [H] COG0502 Biotin synthase and related enzymes. | 0.833 |
| AQM60963.1 | hydF | NPD11_1861 | NPD11_2811 | [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain. | GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF; [R] COG1160 Predicted GTPases. | 0.779 |