STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hydGrSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (459 aa)    
Predicted Functional Partners:
hydF
GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF; [R] COG1160 Predicted GTPases.
  
 0.968
hydG-2
rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
 
  
 
0.967
AQM60523.1
Hypothetical protein.
 
   
 0.904
hydE
rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE; [H] COG0502 Biotin synthase and related enzymes.
 
  
0.859
AQM60963.1
[R] COG4624 Iron only hydrogenase large subunit, C-terminal domain.
 
   
 0.758
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.714
AQM60659.1
Hypothetical protein; Iron only hydrogenase large subunit, C-terminal domain protein; [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain.
 
   
 0.660
AQM60270.1
Hypothetical protein.
   
    0.544
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
   
    0.544
thiM
Hydroxyethylthiazole kinase family protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
  
 0.508
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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