Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hydFGTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF; [R] COG1160 Predicted GTPases. (399 aa)    
Predicted Functional Partners:
hydE
rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE; [H] COG0502 Biotin synthase and related enzymes.
   
 0.980
hydG-2
rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
  
 0.970
hydG
rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
  
 0.961
AQM60523.1
Hypothetical protein.
 
    0.907
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
 
 0.828
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 
 0.803
AQM60963.1
[R] COG4624 Iron only hydrogenase large subunit, C-terminal domain.
 
   
 0.779
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.764
rplT
Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
    
 
 0.756
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.756
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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