Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AQM61139.1NAD(P)-binding family protein; [H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). (224 aa)    
Predicted Functional Partners:
cobA
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; [H] COG0007 Uroporphyrinogen-III methylase.
 
 
 0.997
AQM60289.1
cbiX family protein; [H] COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase.
    
 0.967
cobI
Precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
  
 0.948
AQM60082.1
cbiX family protein; [H] COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase.
    
 0.931
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
   
 0.905
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.875
hemL
hemL: glutamate-1-semialdehyde-2,1-aminomutase; [H] COG0001 Glutamate-1-semialdehyde aminotransferase.
 
   
 0.808
AQM60271.1
[H] COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
     
 0.798
AQM58775.1
Helix-turn-helix family protein; [R] COG0457 FOG: TPR repeat.
  
     0.737
AQM59319.1
[P] COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters.
 
   
 0.690
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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