| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NPD11_462 | gpr | NPD11_462 | NPD11_2925 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.567 |
| NPD11_462 | spoIIAB | NPD11_462 | NPD11_2916 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.874 |
| NPD11_462 | spoIID | NPD11_462 | NPD11_1384 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | 0.571 |
| NPD11_462 | spoIIE | NPD11_462 | NPD11_1718 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_II_E: stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit. | 0.947 |
| NPD11_462 | spoIIIAE | NPD11_462 | NPD11_370 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_III_AE: stage III sporulation protein AE. | 0.777 |
| NPD11_462 | spoIIID | NPD11_462 | NPD11_1382 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.811 |
| NPD11_462 | spoIIP | NPD11_462 | NPD11_2926 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_II_P: stage II sporulation P family protein. | 0.855 |
| NPD11_462 | spoIIR | NPD11_462 | NPD11_1413 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_II_R: stage II sporulation protein R. | 0.882 |
| NPD11_462 | spoIVA | NPD11_462 | NPD11_172 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.732 |
| NPD11_462 | yqfD | NPD11_462 | NPD11_2942 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_yqfD: sporulation protein YqfD. | 0.775 |
| gpr | NPD11_462 | NPD11_2925 | NPD11_462 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.567 |
| gpr | spoIIAB | NPD11_2925 | NPD11_2916 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.830 |
| gpr | spoIID | NPD11_2925 | NPD11_1384 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_II_D: stage II sporulation protein D; [D] COG2385 Sporulation protein and related proteins. | 0.499 |
| gpr | spoIIE | NPD11_2925 | NPD11_1718 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_II_E: stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit. | 0.770 |
| gpr | spoIIIAE | NPD11_2925 | NPD11_370 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_III_AE: stage III sporulation protein AE. | 0.769 |
| gpr | spoIIID | NPD11_2925 | NPD11_1382 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.771 |
| gpr | spoIIP | NPD11_2925 | NPD11_2926 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_II_P: stage II sporulation P family protein. | 0.913 |
| gpr | spoIIR | NPD11_2925 | NPD11_1413 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_II_R: stage II sporulation protein R. | 0.770 |
| gpr | spoIVA | NPD11_2925 | NPD11_172 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.833 |
| gpr | yqfD | NPD11_2925 | NPD11_2942 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | spore_yqfD: sporulation protein YqfD. | 0.787 |