| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59049.1 | AQM59107.1 | NPD11_2970 | NPD11_1238 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Hypothetical protein; FAD linked oxidase, C-terminal domain protein; [C] COG0277 FAD/FMN-containing dehydrogenases. | 0.919 |
| AQM59049.1 | AQM60364.1 | NPD11_2970 | NPD11_2969 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Conserved hypothetical protein; [S] COG3862 Uncharacterized protein with conserved CXXC pairs. | 0.531 |
| AQM59049.1 | AQM60665.1 | NPD11_2970 | NPD11_1757 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | [G] COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.933 |
| AQM59049.1 | NPD11_922 | NPD11_2970 | NPD11_922 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Aminotransferase class-III family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.830 |
| AQM59049.1 | cinA | NPD11_2970 | NPD11_2146 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | pncC_: amidohydrolase, PncC family domain protein; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.627 |
| AQM59049.1 | lpdA | NPD11_2970 | NPD11_897 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.424 |
| AQM59049.1 | nnrD | NPD11_2970 | NPD11_2200 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | yjeF-related family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of b [...] | 0.521 |
| AQM59049.1 | pyk | NPD11_2970 | NPD11_1318 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Pyruv_kin: pyruvate kinase; [G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.527 |
| AQM59049.1 | pyk-2 | NPD11_2970 | NPD11_2244 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Pyruv_kin: pyruvate kinase; [G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.527 |
| AQM59049.1 | pyk-3 | NPD11_2970 | NPD11_2347 | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Pyruv_kin: pyruvate kinase; [G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.527 |
| AQM59107.1 | AQM59049.1 | NPD11_1238 | NPD11_2970 | Hypothetical protein; FAD linked oxidase, C-terminal domain protein; [C] COG0277 FAD/FMN-containing dehydrogenases. | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.919 |
| AQM59107.1 | NPD11_922 | NPD11_1238 | NPD11_922 | Hypothetical protein; FAD linked oxidase, C-terminal domain protein; [C] COG0277 FAD/FMN-containing dehydrogenases. | Aminotransferase class-III family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.824 |
| AQM59107.1 | lpdA | NPD11_1238 | NPD11_897 | Hypothetical protein; FAD linked oxidase, C-terminal domain protein; [C] COG0277 FAD/FMN-containing dehydrogenases. | lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.473 |
| AQM60364.1 | AQM59049.1 | NPD11_2969 | NPD11_2970 | Conserved hypothetical protein; [S] COG3862 Uncharacterized protein with conserved CXXC pairs. | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.531 |
| AQM60665.1 | AQM59049.1 | NPD11_1757 | NPD11_2970 | [G] COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.933 |
| NPD11_922 | AQM59049.1 | NPD11_922 | NPD11_2970 | Aminotransferase class-III family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.830 |
| NPD11_922 | AQM59107.1 | NPD11_922 | NPD11_1238 | Aminotransferase class-III family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; FAD linked oxidase, C-terminal domain protein; [C] COG0277 FAD/FMN-containing dehydrogenases. | 0.824 |
| NPD11_922 | lpdA | NPD11_922 | NPD11_897 | Aminotransferase class-III family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.570 |
| cinA | AQM59049.1 | NPD11_2146 | NPD11_2970 | pncC_: amidohydrolase, PncC family domain protein; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | Acetohydroxy acid isomeroreductase, catalytic domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.627 |
| cinA | lpdA | NPD11_2146 | NPD11_897 | pncC_: amidohydrolase, PncC family domain protein; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.449 |