Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NPD11_332Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (288 aa)    
Predicted Functional Partners:
NPD11_331
[NT] COG0840 Methyl-accepting chemotaxis protein.
     
 0.574
AQM60247.1
FAD dependent oxidoreductase family protein; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).
 
 0.573
NPD11_50
X-Pro dipeptidyl-peptidase family protein; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
 0.487
fabD
fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase.
  
 
 0.471
NPD11_334
Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family.
   
   0.470
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.460
lpdA
lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 
 0.457
NPD11_330
Hypothetical protein.
       0.446
NPD11_333
ECF-type riboflavin transporter, S component family protein; [S] COG4720 Predicted membrane protein.
       0.444
thlA
[I] COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.438
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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